SP1 抗体 (pThr453)
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北京 101111
Quick Overview for SP1 抗体 (pThr453) (ABIN1531394)
抗原
See all SP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 421-470, pThr453
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原理
- Sp1 (phospho Thr453) Antibody
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特异性
- Phospho-Sp1 (T453) Polyclonal Antibody detects endogenous levels of Sp1 protein only when phosphorylated at T453.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human SP1 around the phosphorylation site of Thr453. AA range:421-470
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亚型
- IgG
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anti-Sp1 Transcription Factor (SP1) (AA 250-300) antibody
SP1 适用: 人, 小鼠 WB, IHC, ICC, IP 宿主: 兔 Monoclonal BLR354N unconjugated Recombinant Antibody
anti-Sp1 Transcription Factor (SP1) (AA 677-707), (C-Term) antibodySP1 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB17350 unconjugated
anti-Sp1 Transcription Factor (SP1) antibodySP1 适用: 人 WB, IHC, IF, ChIP 宿主: 兔 Monoclonal unconjugated
anti-Sp1 Transcription Factor (SP1) (C-Term) antibodySP1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sp1 Transcription Factor (SP1) (AA 89-198) antibodySP1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1A5 unconjugated
anti-Sp1 Transcription Factor (SP1) (AA 89-198) antibodySP1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4H6 unconjugated
anti-Sp1 Transcription Factor (SP1) (AA 522-618) antibodySP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4B11 unconjugated
anti-Sp1 Transcription Factor (SP1) (AA 89-199) antibodySP1 适用: 人, 小鼠 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4H6 unconjugated
anti-Sp1 Transcription Factor (SP1) (AA 420-620) antibodySP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sp1 Transcription Factor (SP1) antibodyKD Validated SP1 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB7095 unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- SP1 (Sp1 Transcription Factor (SP1))
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别名
- SP1
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背景
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Synonyms: SP1, TSFP1, Transcription factor Sp1
Background: The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014],
Gene Name: SP1
Protein Name: Transcription factor Sp1
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分子量
- 80 kDa
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基因ID
- 6667
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OMIM
- 189906
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UniProt
- P08047
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途径
- Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction
抗原
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