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RPS6 抗体 (pSer6, pSer240)

The 兔 多克隆 anti-RPS6 antibody is suitable to detect RPS6 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IHC, ELISA 和 IF.
产品编号 ABIN1531390
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for RPS6 抗体 (pSer6, pSer240) (ABIN1531390)

抗原

See all RPS6 抗体
RPS6 (Ribosomal Protein S6 (RPS6))

适用

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人, 小鼠, 大鼠

宿主

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兔

克隆类型

  • 153
  • 48
多克隆

标记

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This RPS6 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

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    AA 200-249, pSer6, pSer240

    原理

    Ribosomal Protein S6 (phospho Ser240) Antibody

    特异性

    Phospho-Ribosomal Protein S6 (S240) Polyclonal Antibody detects endogenous levels of Ribosomal Protein S6 protein only when phosphorylated at S240.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human S6 Ribosomal Protein around the phosphorylation site of Ser240. AA range:200-249

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    RPS6 (Ribosomal Protein S6 (RPS6))

    别名

    S6 Ribosomal Protein

    背景

    Synonyms: RPS6, OK/SW-cl.2, 40S ribosomal protein S6, Phosphoprotein NP33

    Background: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins.This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed

    Gene Name: RPS6

    Protein Name: 40S ribosomal protein S6

    分子量

    28 kDa

    基因ID

    6194

    OMIM

    180460

    UniProt

    P62753

    途径

    Carbohydrate Homeostasis, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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