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Progesterone Receptor 抗体 (pSer400)

The 兔 多克隆 anti-Progesterone Receptor antibody is suitable to detect Progesterone Receptor in samples from 人, 大鼠 和 小鼠. It has been validated for WB 和 IHC.
产品编号 ABIN1531381
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Progesterone Receptor 抗体 (pSer400) (ABIN1531381)

抗原

See all Progesterone Receptor (PGR) 抗体
Progesterone Receptor (PGR)

适用

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人, 大鼠, 小鼠

宿主

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兔

克隆类型

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多克隆

标记

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This Progesterone Receptor antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
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    AA 371-420, pSer400

    原理

    PR (phospho Ser400) Antibody

    特异性

    Phospho-PR (S400) Polyclonal Antibody detects endogenous levels of PR protein only when phosphorylated at S400.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human Progesterone Receptor around the phosphorylation site of Ser400. AA range:371-420

    亚型

    IgG
  • 应用备注

    WB 1:500-2000,IHC 1:50-300

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Progesterone Receptor (PGR)

    别名

    Progesterone Receptor

    背景

    Synonyms: PGR, NR3C3, Progesterone receptor, PR, Nuclear receptor subfamily 3 group C member 3

    Background: This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. [provided by RefSeq, Sep 2015],

    Gene Name: PGR

    Protein Name: Progesterone receptor

    分子量

    98 kDa

    基因ID

    5241

    OMIM

    607311

    UniProt

    P06401

    途径

    Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration
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