MYB 抗体 (pSer12)
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北京 101111
Quick Overview for MYB 抗体 (pSer12) (ABIN1531346)
抗原
See all MYB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-50, pSer12
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原理
- c-Myb (phospho Ser12) Antibody
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特异性
- Phospho-c-Myb (S12) Polyclonal Antibody detects endogenous levels of c-Myb protein only when phosphorylated at S12.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human MYB around the phosphorylation site of Ser12. AA range:1-50
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))
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别名
- MYB
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背景
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Synonyms: MYB, Transcriptional activator Myb, Proto-oncogene c-Myb
Background: This gene encodes a protein with three HTH DNA-binding domains that functions as a transcription regulator. This protein plays an essential role in the regulation of hematopoiesis. This gene may be aberrently expressed or rearranged or undergo translocation in leukemias and lymphomas, and is considered to be an oncogene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],
Gene Name: MYB
Protein Name: Transcriptional activator Myb
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分子量
- 72 kDa
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基因ID
- 4602
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OMIM
- 189990
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UniProt
- P10242
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途径
- Chromatin Binding, Positive Regulation of Immune Effector Process
抗原
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