FOXO1 抗体 (pThr24, pThr32)
Our Local Distributor
北京 101111
Quick Overview for FOXO1 抗体 (pThr24, pThr32) (ABIN1531320)
抗原
See all FOXO1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 15-64, pThr24, pThr32
-
原理
- FoxO1/3/4 (phospho Thr24/32) Antibody
-
特异性
- Phospho-FoxO1/3/4 (T24/32) Polyclonal Antibody detects endogenous levels of FoxO1/3/4 protein only when phosphorylated at T24/32.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
纯度
- > 95 %
-
免疫原
- The antiserum was produced against synthesized peptide derived from human FOXO1/3/4-pan around the phosphorylation site of Thr24/32. AA range:15-64
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- FOXO1 (Forkhead Box O1 (FOXO1))
-
别名
- FOXO1/3/4
-
背景
-
Synonyms: FOXO1, FKHR, FOXO1A, Forkhead box protein O1, Forkhead box protein O1A, Forkhead in rhabdomyosarcoma, FOXO3, FKHRL1, FOXO3A, Forkhead box protein O3, AF6q21 protein, Forkhead in rhabdomyosarcoma-like 1, FOXO4, AFX, AFX1, MLLT7, Forkhead box
Background: This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined, however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. [provided by RefSeq, Jul 2008],
Gene Name: FOXO1/3/4
Protein Name: Forkhead box protein O1/3/4
-
分子量
- 69 kDa
-
基因ID
- 2308, 4303
-
OMIM
- 136533
-
UniProt
- Q12778
-
途径
- PI3K-Akt Signaling, Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, CXCR4-mediated Signaling Events, BCR Signaling
抗原
-