Aurora A 抗体 (pThr288)
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北京 101111
Quick Overview for Aurora A 抗体 (pThr288) (ABIN1531301)
抗原
See all Aurora A (AURKA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 256-305, pThr288
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原理
- ARK-1 (phospho Thr288) Antibody
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特异性
- Phospho-ARK-1 (T288) Polyclonal Antibody detects endogenous levels of ARK-1 protein only when phosphorylated at T288.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Aurora Kinase around the phosphorylation site of Thr288. AA range:256-305
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Aurora A (AURKA) (Aurora Kinase A (AURKA))
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背景
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Synonyms: AURKA, AIK, AIRK1, ARK1, AURA, AYK1, BTAK, IAK1, STK15, STK6, Aurora kinase A, Aurora 2, Aurora/IPL1-related kinase 1, ARK-1, Aurora-related kinase 1, hARK1, Breast tumor-amplified kinase, Serine/threonine-protein kinase 15, Serine/threonin
Background: The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],
Gene Name: AURKA
Protein Name: Aurora kinase A
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分子量
- 45 kDa
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基因ID
- 6790
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OMIM
- 603072
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UniProt
- O14965
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途径
- Cell Division Cycle, Asymmetric Protein Localization
抗原
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