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WNK1 抗体 (pThr58)

The 兔 多克隆 anti-WNK1 antibody is suitable to detect WNK1 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IHC, ELISA 和 IF.
产品编号 ABIN1531249
发货至: 中国
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北京 101111
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for WNK1 抗体 (pThr58) (ABIN1531249)

抗原

See all WNK1 抗体
WNK1 (WNK Lysine Deficient Protein Kinase 1 (WNK1))

适用

  • 108
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  • 1
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人, 小鼠, 大鼠

宿主

  • 108
  • 1
兔

克隆类型

  • 87
  • 22
多克隆

标记

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This WNK1 antibody is un-conjugated

应用范围

  • 45
  • 38
  • 25
  • 13
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  • 10
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  • 8
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 15
    • 12
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    • 6
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    • 4
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    • 1
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    AA 24-73, pThr58

    原理

    WNK1 (phospho Thr60) Antibody

    特异性

    Phospho-WNK1 (T60) Polyclonal Antibody detects endogenous levels of WNK1 protein only when phosphorylated at T60.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human WNK1 around the phosphorylation site of Thr58. AA range:24-73

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    WNK1 (WNK Lysine Deficient Protein Kinase 1 (WNK1))

    别名

    WNK1

    背景

    Synonyms: WNK1, HSN2, KDP, KIAA0344, PRKWNK1, Serine/threonine-protein kinase WNK1, Erythrocyte 65 kDa protein, p65, Kinase deficient protein, Protein kinase lysine-deficient 1, Protein kinase with no lysine 1, hWNK1

    Background: This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions. Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II. Alternatively spliced transcript variants encoding different isoforms have been described but the full-length nature of all of them has yet to be determined.[provided by RefSeq, May 2010],

    Gene Name: WNK1

    Protein Name: Serine/threonine-protein kinase WNK1

    分子量

    250 kDa

    基因ID

    65125

    OMIM

    145260

    UniProt

    Q9H4A3
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