WNK1 抗体 (pThr58)
Our Local Distributor
北京 101111
Quick Overview for WNK1 抗体 (pThr58) (ABIN1531249)
抗原
See all WNK1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 24-73, pThr58
-
原理
- WNK1 (phospho Thr60) Antibody
-
特异性
- Phospho-WNK1 (T60) Polyclonal Antibody detects endogenous levels of WNK1 protein only when phosphorylated at T60.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
纯度
- > 95 %
-
免疫原
- The antiserum was produced against synthesized peptide derived from human WNK1 around the phosphorylation site of Thr58. AA range:24-73
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- WNK1 (WNK Lysine Deficient Protein Kinase 1 (WNK1))
-
别名
- WNK1
-
背景
-
Synonyms: WNK1, HSN2, KDP, KIAA0344, PRKWNK1, Serine/threonine-protein kinase WNK1, Erythrocyte 65 kDa protein, p65, Kinase deficient protein, Protein kinase lysine-deficient 1, Protein kinase with no lysine 1, hWNK1
Background: This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions. Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II. Alternatively spliced transcript variants encoding different isoforms have been described but the full-length nature of all of them has yet to be determined.[provided by RefSeq, May 2010],
Gene Name: WNK1
Protein Name: Serine/threonine-protein kinase WNK1
-
分子量
- 250 kDa
-
基因ID
- 65125
-
OMIM
- 145260
-
UniProt
- Q9H4A3
抗原
-