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KRT8 抗体 (pSer73)

The 兔 多克隆 anti-KRT8 antibody is suitable to detect KRT8 in samples from 人 和 小鼠. It has been validated for WB, IHC, IF 和 ELISA.
产品编号 ABIN1531186
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for KRT8 抗体 (pSer73) (ABIN1531186)

抗原

See all KRT8 抗体
KRT8 (Keratin 8 (KRT8))

适用

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人, 小鼠

宿主

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兔

克隆类型

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多克隆

标记

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This KRT8 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA
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    AA 41-90, pSer73

    原理

    Cytokeratin 8 (phospho Ser73) Antibody

    特异性

    Phospho-Cytokeratin 8 (S73) Polyclonal Antibody detects endogenous levels of Cytokeratin 8 protein only when phosphorylated at S73.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human Keratin 8 around the phosphorylation site of Ser73. AA range:41-90

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    KRT8 (Keratin 8 (KRT8))

    别名

    Keratin 8

    背景

    Synonyms: KRT8, CYK8, Keratin, type II cytoskeletal 8, Cytokeratin-8, CK-8, Keratin-8, K8, Type-II keratin Kb8

    Background: keratin 8(KRT8) Homo sapiens This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012],

    Gene Name: KRT8

    Protein Name: Keratin type II cytoskeletal 8

    分子量

    53 kDa

    基因ID

    3856

    OMIM

    148060

    UniProt

    P05787
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