KRT8 抗体
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- 抗原 See all KRT8 抗体
- KRT8 (Keratin 8 (KRT8))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This KRT8 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 纯化方法
- Protein-A affinity chromatography
- 克隆位点
- AT3D11
- 亚型
- IgG3
- Top Product
- Discover our top product KRT8 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate-Buffered Saline ( pH 7.4) containing 10 % Glycerol, 0.02 % Sodium Azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- 抗原
- KRT8 (Keratin 8 (KRT8))
- 别名
- Cytokeratin 8 (KRT8 产品)
- 背景
- Keratin, type II cytoskeletal 8 also known as cytokeratin-8 (CK-8) or keratin-8 (K8) is a keratin protein that in human is encoded by the KRT8 gene. This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.Synonyms: CK8, CYK8, Cytokeratin endo A, Cytokeratin-8, K8, KRT8, Keratin, Keratin-8, type II cytoskeletal 8
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