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HBG1/2 抗体

适用: 人 IF, WB 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7101335
发货至: 中国
  • 抗原
    HBG1/2
    适用
    宿主
    • 1
    克隆类型
    • 1
    单克隆
    标记
    • 1
    非结合性
    应用范围
    • 1
    • 1
    • 1
    Immunofluorescence (IF), Western Blotting (WB)
    交叉反应
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human HBG1
    亚型
    IgG
  • 应用备注
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid freeze / thaw cycles
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    HBG1/2
    背景
    The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008],HBG-T2, HBGA, HBGR, HSGGL1, PRO2979,HBG1/2
    分子量
    12 kDa
    基因ID
    3047, 3048
    UniProt
    P69891, P69892
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