CYP2D6 抗体 (AA 20-230)
Quick Overview for CYP2D6 抗体 (AA 20-230) (ABIN1512811)
抗原
See all CYP2D6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 20-230
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序列
- VDLMHRRQRW AARYPPGPLP LPGLGNLLHV DFQNTPYCFD QLRRRFGDVF SLQLAWTPVV VLNGLAAVRE ALVTHGEDTA DRPPVPITQI LGFGPRSQGV FLARYGPAWR EQRRFSVSTL RNLGLGKKSL EQWVTEEAAC LCAAFANHSG RPFRPNGLLD KAVSNVIASL TCGRRFEYDD PRFLRLLDLA QEGLKEESGF LREVLNAVPV L
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 20-230 of human CYP2D6 (NP_000097.3).
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亚型
- IgG
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anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) (AA 236-472) antibody
CYP2D6 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) (AA 315-347), (C-Term) antibodyCYP2D6 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) antibodyCYP2D6 适用: 人, 大鼠, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) (AA 268-457) antibodyCYP2D6 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) (AA 315-347) antibodyCYP2D6 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) (AA 1-497) antibodyCYP2D6 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) (AA 91-190) antibodyCYP2D6 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2C5 unconjugated
anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) (AA 101-150) antibodyCYP2D6 适用: 人, 猴, 绵羊, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) (N-Term) antibodyCYP2D6 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) (AA 101-210) antibodyCYP2D6 适用: 人, 大鼠, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:100 - 1:500,IHC,1:20 - 1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- CYP2D6 (Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6))
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别名
- CYP2D6
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背景
- This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 25 % of commonly prescribed drugs. Its substrates include antidepressants, antipsychotics, analgesics and antitussives, beta adrenergic blocking agents, antiarrythmics and antiemetics. The gene is highly polymorphic in the human population, certain alleles result in the poor metabolizer phenotype, characterized by a decreased ability to metabolize the enzyme's substrates. Some individuals with the poor metabolizer phenotype have no functional protein since they carry 2 null alleles whereas in other individuals the gene is absent. This gene can vary in copy number and individuals with the ultrarapid metabolizer phenotype can have 3 or more active copies of the gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,CYP2D6,CPD6,CYP2D,CYP2D7AP,CYP2D7BP,CYP2D7P2,CYP2D8P2,CYP2DL1,CYPIID6,P450-DB1,P450C2D,P450DB1,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Cytochromes,Lipid Metabolism,Cytochromes,Lipases,Drug metabolism,Cardiovascular,Lipids,CYP2D6
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分子量
- 50 kDa/55 kDa
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基因ID
- 1565
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UniProt
- P10635
抗原
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