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BMP2 抗体 (AA 283-396)

This anti-BMP2 antibody is a 兔 多克隆 antibody detecting BMP2 in WB, IHC 和 IF. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN1513827
发货至: 中国

Quick Overview for BMP2 抗体 (AA 283-396) (ABIN1513827)

抗原

See all BMP2 抗体
BMP2 (Bone Morphogenetic Protein 2 (BMP2))

适用

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宿主

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克隆类型

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多克隆

标记

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This BMP2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 283-396

    序列

    QAKHKQRKRL KSSCKRHPLY VDFSDVGWND WIVAPPGYHA FYCHGECPFP LADHLNSTNH AIVQTLVNSV NSKIPKACCV PTELSAISML YLDENEKVVL KNYQDMVVEG CGCR

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 283-396 of human BMP2 (NP_001191.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Wang, Zhou, Zhang, Shi, Xiao, Zeng, Yang, Zheng, Wang, Mai: "BMP2 promotes proliferation and invasion of nasopharyngeal carcinoma cells via mTORC1 pathway." in: Aging, Vol. 9, Issue 4, pp. 1326-1340, (2018) (PubMed).

  • 抗原

    BMP2 (Bone Morphogenetic Protein 2 (BMP2))

    别名

    BMP2

    背景

    This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients.,BDA2,BMP2A,BMP2,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Bone,Growth factor,TGF-b-Smad Signaling Pathway,Wnt/β-Catenin Signaling Pathway,ESC Pluripotency and Differentiation,Immunology & Inflammation,Cytokines,NF-kB Signaling Pathway,Stem Cells,Neural Stem Cells,Cardiovascular,Angiogenesis,Ligand,BMP2

    分子量

    44 kDa

    基因ID

    650

    UniProt

    P12643

    途径

    Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Growth Factor Binding, Positive Regulation of fat Cell Differentiation
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