MAFK 抗体
Quick Overview for MAFK 抗体 (ABIN1504391)
抗原
See all MAFK 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Protein-A affinity chromatography
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亚型
- IgG2a
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anti-Transcription Factor MafK (MAFK) antibody
MAFK 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 8C5 unconjugated
anti-Transcription Factor MafK (MAFK) (N-Term) antibodyMAFK 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 斑马鱼, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor MafK (MAFK) (N-Term) antibodyMAFK 适用: 人, 小鼠, 豚鼠, Hamster, 猴, 小鸡, 非洲爪蟾, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor MafK (MAFK) (N-Term) antibodyMAFK 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 犬, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor MafK (MAFK) (N-Term) antibodyMAFK 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate-Buffered Saline ( pH 7.4) containing 10 % Glycerol, 0.02 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- MAFK (Transcription Factor MafK (MAFK))
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别名
- MAFK
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背景
- The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2 (nuclear factor erythroid-2). NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG or MafK) and p45. Since Maf homodimers lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. The MafK of Maf proteins is primarily expressed during development in mesenchymal and hematopoietic cells and neurons.Synonyms: Transcription factor MafK, v-maf musculoaponeurotic fibrosarcoma oncogene homolog K
抗原
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