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UCP3 抗体 (AA 259-308)

The 兔 多克隆 anti-UCP3 antibody (ABIN1454058) specifically detects UCP3 in WB 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN1454058
发货至: 中国
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Quick Overview for UCP3 抗体 (AA 259-308) (ABIN1454058)

抗原

See all UCP3 抗体
UCP3 (Uncoupling Protein 3 (Mitochondrial, Proton Carrier) (UCP3))

适用

  • 49
  • 38
  • 30
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 51
  • 1
  • 1
兔

克隆类型

  • 52
  • 1
多克隆

标记

  • 25
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This UCP3 antibody is un-conjugated

应用范围

  • 33
  • 16
  • 9
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 12
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 259-308

    原理

    UCP3 Antibody

    特异性

    UCP3 Polyclonal Antibody detects endogenous levels of UCP3 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized peptide derived from human UCP3. AA range:259-308

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    UCP3 (Uncoupling Protein 3 (Mitochondrial, Proton Carrier) (UCP3))

    别名

    UCP3

    背景

    Synonyms: UCP3; SLC25A9; Mitochondrial uncoupling protein 3; UCP 3; Solute carrier family 25 member 9

    Background: Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. The different UCPs have tissue-specific expression; this gene is primarily expressed in skeletal muscle. This gene's protein product is postulated to protect mitochondria against lipid-induced oxidative stress. Expression levels of this gene increase when fatty acid supplies to mitochondria exceed their oxidation capacity and the protein enables the export of fatty acids from mitochondria.

    Gene Name: UCP3

    Protein Name: Mitochondrial uncoupling protein 3

    分子量

    34 kDa

    基因ID

    7352

    OMIM

    602044

    UniProt

    P55916

    途径

    Proton Transport
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