Uromodulin 抗体 (AA 329-378)
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北京 101111
Quick Overview for Uromodulin 抗体 (AA 329-378) (ABIN1453998)
抗原
See all Uromodulin (UMOD) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 329-378
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原理
- THP Antibody
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特异性
- THP Polyclonal Antibody detects endogenous levels of THP protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human THP. AA range:329-378
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亚型
- IgG
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anti-Uromodulin (UMOD) (AA 351-450) antibody
UMOD 适用: 人 WB, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Uromodulin (UMOD) (AA 25-120) antibodyUMOD 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3F10 unconjugated
anti-Uromodulin (UMOD) (AA 32-151) antibodyUMOD 适用: 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Uromodulin (UMOD) (AA 1-611) antibodyUMOD 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Uromodulin (UMOD) (AA 1-611) antibodyUMOD 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Uromodulin (UMOD) antibodyUMOD 适用: 人, 犬 IHC, IF, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal 10-32 unconjugated
anti-Uromodulin (UMOD) (AA 334-589) antibodyUMOD 适用: 人 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Uromodulin (UMOD) (C-Term) antibodyUMOD 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Uromodulin (UMOD) (C-Term) antibodyVerified UMOD 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Uromodulin (UMOD) (AA 525-536) antibodyVerified UMOD 适用: 人 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
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应用备注
- WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Uromodulin (UMOD)
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别名
- THP
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背景
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Synonyms: UMOD, Uromodulin, Tamm-Horsfall urinary glycoprotein, THP
Background: The protein encoded by this gene is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2), glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI), and familial juvenile hyperuricemic nephropathy (FJHN). Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2013],
Gene Name: UMOD
Protein Name: Uromodulin
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分子量
- 69 kDa
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基因ID
- 7369
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OMIM
- 191845
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UniProt
- P07911
抗原
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