Peroxiredoxin 3 抗体 (AA 44-93)
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Quick Overview for Peroxiredoxin 3 抗体 (AA 44-93) (ABIN1453824)
抗原
See all Peroxiredoxin 3 (PRDX3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 44-93
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原理
- PRX III Antibody
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特异性
- PRX III Polyclonal Antibody detects endogenous levels of PRX III protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human PRX III. AA range:44-93
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000.IHC:1:50-300 IP 1:50-200 ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Peroxiredoxin 3 (PRDX3)
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别名
- PRX III
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背景
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Synonyms: PRDX3, AOP1, Thioredoxin-dependent peroxide reductase, mitochondrial, Antioxidant protein 1, AOP-1, HBC189, Peroxiredoxin III, Prx-III, Peroxiredoxin-3, Protein MER5 homolog
Background: This gene encodes a mitochondrial protein with antioxidant function. The protein is similar to the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase, and it can rescue bacterial resistance to alkylhydroperoxide in E. coli that lack the C22 subunit. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologs suggest that these genes consist of a family that is responsible for the regulation of cellular proliferation, differentiation and antioxidant functions. This family member can protect cells from oxidative stress, and it can promote cell survival in prostate cancer. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 3, 13 and 22. [provided by RefSeq, Oct 2014],
Gene Name: PRDX3
Protein Name: Thioredoxin-dependent peroxide reductase mitochondrial
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分子量
- 27 kDa
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基因ID
- 10935
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OMIM
- 604769
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UniProt
- P30048
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途径
- Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process
抗原
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