SLC26A5 抗体
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北京 101111
Quick Overview for SLC26A5 抗体 (ABIN1453815)
抗原
See all SLC26A5 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- S26A5 Antibody
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特异性
- This antibody detects endogenous levels of human S26A5
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human S26A5
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亚型
- IgG
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应用备注
- WB 1:500-2000 IHC 1:100-500. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- SLC26A5 (Solute Carrier Family 26, Member 5 (Prestin) (SLC26A5))
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别名
- Prestin
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背景
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Synonyms: Prestin (Solute carrier family 26 member 5)
Background: This gene encodes a member of the SLC26A/SulP transporter family. The protein functions as a molecular motor in motile outer hair cells (OHCs) of the cochlea, inducing changes in cell length that act to amplify sound levels. The transmembrane protein is an incomplete anion transporter, and does not allow anions to cross the cell membrane but instead undergoes a conformational change in response to changes in intracellular Cl- levels that results in a change in cell length. The protein functions at microsecond rates, which is several orders of magnitude faster than conventional molecular motor proteins. Mutations in this gene are potential candidates for causing neurosensory deafness. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2009],
Gene Name: SLC26A5 PRES
Protein Name: S26A5
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分子量
- 81 kDa
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基因ID
- 375611
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OMIM
- 604943
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UniProt
- P58743
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途径
- Sensory Perception of Sound, Dicarboxylic Acid Transport
抗原
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