Interleukin enhancer-binding factor 3 (ILF3) (AA 302-351) 抗体
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Quick Overview for Interleukin enhancer-binding factor 3 (ILF3) (AA 302-351) 抗体 (ABIN1453638)
抗原
See all Interleukin enhancer-binding factor 3 (ILF3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 302-351
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原理
- NF90 Antibody
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特异性
- NF90 Polyclonal Antibody detects endogenous levels of NF90 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human NF90. AA range:302-351
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Interleukin enhancer-binding factor 3 (ILF3)
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别名
- NF90
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背景
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Synonyms: ILF3, DRBF, MPHOSPH4, NF90, Interleukin enhancer-binding factor 3, Double-stranded RNA-binding protein 76, DRBP76, M-phase phosphoprotein 4, MPP4, Nuclear factor associated with dsRNA, NFAR, Nuclear factor of activated T-cells 90 kDa, NF-AT-90, Translational control protein 80, TCP80
Background: This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2014],
Gene Name: ILF3
Protein Name: Interleukin enhancer-binding factor 3
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分子量
- 95 kDa
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基因ID
- 3609
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OMIM
- 603182
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UniProt
- Q12906
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途径
- M Phase
抗原
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