MFN2 抗体 (AA 354-403)
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北京 101111
Quick Overview for MFN2 抗体 (AA 354-403) (ABIN1453569)
抗原
See all MFN2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 354-403
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原理
- Mfn2 Antibody
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特异性
- Mfn2 Polyclonal Antibody detects endogenous levels of Mfn2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human Mfn2. AA range:354-403
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000. IF 1:100-300 Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- MFN2 (Mitofusin 2 (MFN2))
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别名
- Mfn2
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背景
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Synonyms: MFN2, CPRP1, KIAA0214, Mitofusin-2, Transmembrane GTPase MFN2
Background: This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008],
Gene Name: MFN2
Protein Name: Mitofusin-2
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分子量
- 86 kDa
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基因ID
- 9927
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OMIM
- 608507
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UniProt
- O95140
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途径
- Skeletal Muscle Fiber Development
抗原
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