HIF3A 抗体 (AA 305-354)
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Quick Overview for HIF3A 抗体 (AA 305-354) (ABIN1453401)
抗原
See all HIF3A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 305-354
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原理
- HIF-3α Antibody
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特异性
- HIF-3α Polyclonal Antibody detects endogenous levels of HIF-3α protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human HIF-3alpha. AA range:305-354
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))
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别名
- HIF-3Alpha
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背景
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Synonyms: Hypoxia-inducible factor 3-alpha, HIF-3-alpha, HIF3-alpha, Basic-helix-loop-helix-PAS protein MOP7, Class E basic helix-loop-helix protein 17, bHLHe17, HIF3-alpha-1, Inhibitory PAS domain protein, IPAS, Member of PAS protein 7, PAS domain-c
Background: hypoxia inducible factor 3 alpha subunit(HIF3A) Homo sapiens The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2011],
Gene Name: HIF3A
Protein Name: Hypoxia-inducible factor 3-alpha
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分子量
- 72 kDa
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基因ID
- 64344
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OMIM
- 609976
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UniProt
- Q66K72
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途径
- Warburg Effect
抗原
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