Cytohesin 3 抗体 (AA 351-400)
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北京 101111
Quick Overview for Cytohesin 3 抗体 (AA 351-400) (ABIN1453377)
抗原
See all Cytohesin 3 (CYTH3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 351-400
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原理
- GRP1 Antibody
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特异性
- GRP1 Polyclonal Antibody detects endogenous levels of GRP1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human GRP1. AA range:351-400
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Cytohesin 3 (CYTH3)
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别名
- GRP1
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背景
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Synonyms: CYTH3, ARNO3, GRP1, PSCD3, Cytohesin-3, ARF nucleotide-binding site opener 3, Protein ARNO3, General receptor of phosphoinositides 1, Grp1, PH, SEC7 and coiled-coil domain-containing protein 3
Background: This gene encodes a member of the PSCD (pleckstrin homology, Sec7 and coiled-coil domains) family. PSCD family members have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This encoded protein is involved in the control of Golgi structure and function, and it may have a physiological role in regulating ADP-ribosylation factor protein 6 (ARF) functions, in addition to acting on ARF1. [provided by RefSeq, Jul 2008],
Gene Name: CYTH3
Protein Name: Cytohesin-3
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分子量
- 46 kDa
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基因ID
- 9265
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OMIM
- 605081
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UniProt
- O43739
抗原
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