FTO 抗体 (AA 19-68)
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北京 101111
Quick Overview for FTO 抗体 (AA 19-68) (ABIN1453296)
抗原
See all FTO 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 19-68
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原理
- FTO Antibody
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特异性
- FTO Polyclonal Antibody detects endogenous levels of FTO protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human FTO. AA range:19-68
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- FTO (Fat Mass and Obesity-Associated (FTO))
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别名
- FTO
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背景
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Synonyms: FTO, KIAA1752, Alpha-ketoglutarate-dependent dioxygenase FTO, Fat mass and obesity-associated protein
Background: This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011],
Gene Name: FTO
Protein Name: Alpha-ketoglutarate-dependent dioxygenase FTO
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分子量
- 58 kDa
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基因ID
- 79068
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OMIM
- 610966
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UniProt
- Q9C0B1
抗原
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