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EEA1 抗体 (AA 205-254)

The 兔 多克隆 anti-EEA1 antibody (ABIN1453230) specifically detects EEA1 in WB 和 ELISA. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN1453230
发货至: 中国
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Quick Overview for EEA1 抗体 (AA 205-254) (ABIN1453230)

抗原

See all EEA1 抗体
EEA1 (Early Endosome Antigen 1 (EEA1))

适用

  • 98
  • 60
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  • 3
  • 1
  • 1
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  • 1
人, 小鼠

宿主

  • 81
  • 14
  • 3
  • 1
  • 1
兔

克隆类型

  • 73
  • 27
多克隆

标记

  • 49
  • 6
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  • 3
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  • 3
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  • 3
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  • 1
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  • 1
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This EEA1 antibody is un-conjugated

应用范围

  • 62
  • 32
  • 26
  • 26
  • 17
  • 13
  • 13
  • 9
  • 6
  • 4
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 16
    • 15
    • 6
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    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
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    • 1
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    • 1
    • 1
    AA 205-254

    原理

    EEA1 Antibody

    特异性

    EEA1 Polyclonal Antibody detects endogenous levels of EEA1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized peptide derived from human EEA1. AA range:205-254

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    EEA1 (Early Endosome Antigen 1 (EEA1))

    别名

    EEA1

    背景

    Synonyms: EEA1, ZFYVE2, Early endosome antigen 1, Endosome-associated protein p162, Zinc finger FYVE domain-containing protein 2

    Background: disease:Antibodies against EEA1 are found in sera from patients with subacute cutaneous lupus erythematosus and other autoimmune diseases.,domain:The FYVE-type zinc finger domain mediates interactions with phosphatidylinositol 3-phosphate.,function:Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking.,similarity:Contains 1 C2H2-type zinc finger.,similarity:Contains 1 FYVE-type zinc finger.,subunit:Homodimer. Binds STX6. Binds RAB5A, RAB5B, RAB5C and RAB22A that have been activated by GTP-binding.,

    Gene Name: EEA1

    Protein Name: Early endosome antigen 1

    分子量

    162 kDa

    基因ID

    8411

    OMIM

    605070

    UniProt

    Q15075

    途径

    Toll-Like Receptors Cascades
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