E2F5 抗体 (AA 93-142)
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北京 101111
Quick Overview for E2F5 抗体 (AA 93-142) (ABIN1453215)
抗原
See all E2F5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 93-142
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原理
- E2F-5 Antibody
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特异性
- E2F-5 Polyclonal Antibody detects endogenous levels of E2F-5 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human E2F-5. AA range:93-142
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- E2F5
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别名
- E2F-5
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背景
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Synonyms: E2F5, Transcription factor E2F5, E2F-5
Background: The protein encoded byThis gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains that are present in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein is differentially phosphorylated and is expressed in a wide variety of human tissues. It has higher identity to E2F4 than to other family members. Both this protein and E2F4 inter
Gene Name: E2F5
Protein Name: Transcription factor E2F5
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分子量
- 37 kDa
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基因ID
- 1875
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OMIM
- 600967
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UniProt
- Q15329
抗原
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