DEFa3 抗体 (AA 3-52)
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北京 101111
Quick Overview for DEFa3 抗体 (AA 3-52) (ABIN1453197)
抗原
See all DEFa3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 3-52
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原理
- Defensin α3 Antibody
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特异性
- Defensin α3 Polyclonal Antibody detects endogenous levels of Defensin α3 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human Defensin alpha3. AA range:3-52
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亚型
- IgG
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应用备注
- IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- DEFa3 (Defensin, alpha 3, Neutrophil-Specific (DEFa3))
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别名
- Defensin Alpha3
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背景
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Synonyms: DEFA3, DEF3, Neutrophil defensin 3, Defensin, alpha 3, HNP-3, HP-3, HP3
Background: defensin alpha 3(DEFA3) Homo sapiens Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif.The protein encoded by this gene, defensin, alpha 3, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 1 by only one amino acid. This gene and the gene encoding defensin, alpha 1 are both subject to copy number variation. [provided by RefSeq, Oct 2014],
Gene Name: DEFA3
Protein Name: Neutrophil defensin 3
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分子量
- 10 kDa
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基因ID
- 1668
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OMIM
- 604522
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UniProt
- P59666
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途径
- Cellular Response to Molecule of Bacterial Origin
抗原
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