alpha Defensin 1 抗体 (AA 3-52)
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Quick Overview for alpha Defensin 1 抗体 (AA 3-52) (ABIN1453194)
抗原
See all alpha Defensin 1 (DEFA1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 3-52
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原理
- Defensin α1 Antibody
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特异性
- Defensin α1 Polyclonal Antibody detects endogenous levels of Defensin α1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human Defensin alpha1. AA range:3-52
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亚型
- IgG
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应用备注
- IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- alpha Defensin 1 (DEFA1) (Defensin, alpha 1 (DEFA1))
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别名
- Defensin Alpha1
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背景
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Synonyms: DEFA1, DEF1, DEFA2, MRS, DEFA1B, Neutrophil defensin 1, Defensin, alpha 1, HNP-1, HP-1, HP1
Background: defensin alpha 1(DEFA1) Homo sapiens Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif.The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation. [provided by RefSeq, Oct 2014],
Gene Name: DEFA1
Protein Name: Neutrophil defensin 1
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分子量
- 10 kDa
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基因ID
- 1667
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OMIM
- 125220
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UniProt
- P59665
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途径
- Cellular Response to Molecule of Bacterial Origin
抗原
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