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CRH 抗体 (AA 104-153)

The 兔 多克隆 anti-CRH antibody (ABIN1453167) specifically detects CRH in IHC, ELISA 和 IF. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN1453167
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
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Quick Overview for CRH 抗体 (AA 104-153) (ABIN1453167)

抗原

See all CRH 抗体
CRH (Corticotropin Releasing Hormone (CRH))

适用

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人, 大鼠, 小鼠

宿主

  • 89
  • 23
  • 2
  • 2
兔

克隆类型

  • 95
  • 21
多克隆

标记

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This CRH antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 20
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    AA 104-153

    原理

    CRF Antibody

    特异性

    CRF Polyclonal Antibody detects endogenous levels of CRF protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized peptide derived from human CRF. AA range:104-153

    亚型

    IgG
  • 应用备注

    IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    CRH (Corticotropin Releasing Hormone (CRH))

    别名

    CRF

    背景

    Synonyms: CRH; Corticoliberin; Corticotropin-releasing factor; CRF; Corticotropin-releasing hormone

    Background: This gene encodes a member of the corticotropin-releasing factor family. The encoded preproprotein is proteolytically processed to generate the mature neuropeptide hormone. In response to stress, this hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus, binds to corticotropin releasing hormone receptors and stimulates the release of adrenocorticotropic hormone from the pituitary gland. Marked reduction in this protein has been observed in association with Alzheimer's disease. Autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes, and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation a

    Gene Name: CRH

    Protein Name: Corticoliberin

    分子量

    21 kDa

    基因ID

    1392

    OMIM

    122560

    UniProt

    P06850

    途径

    Positive Regulation of Peptide Hormone Secretion, Hormone Activity, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Feeding Behaviour
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