COX10 抗体 (AA 98-147)
Our Local Distributor
北京 101111
Quick Overview for COX10 抗体 (AA 98-147) (ABIN1453164)
抗原
See all COX10 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 98-147
-
原理
- COX10 Antibody
-
特异性
- COX10 Polyclonal Antibody detects endogenous levels of COX10 protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- The antiserum was produced against synthesized peptide derived from human COX10. AA range:98-147
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- COX10 (Cytochrome C Oxidase Assembly Homolog 10 (COX10))
-
别名
- COX10
-
背景
-
Synonyms: COX10, Protoheme IX farnesyltransferase, mitochondrial, Heme O synthase
Background: Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes heme A:farnesyltransferase, which is not a structural subunit but required for the expression of functional COX and functions in the maturation of the heme A prosthetic group of COX. This protein is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane. A gene mutation, which results in the substitution of a lys
Gene Name: COX10
Protein Name: Protoheme IX farnesyltransferase mitochondrial
-
分子量
- 48 kDa
-
基因ID
- 1352
-
OMIM
- 602125
-
UniProt
- Q12887
抗原
-