Chromogranin A 抗体 (AA 311-360)
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北京 101111
Quick Overview for Chromogranin A 抗体 (AA 311-360) (ABIN1453137)
抗原
See all Chromogranin A (CHGA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 311-360
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原理
- Chr-A Antibody
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特异性
- Chr-A Polyclonal Antibody detects endogenous levels of Chr-A protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human Chr-A. AA range:311-360
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Chromogranin A (CHGA)
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背景
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Synonyms: CHGA, Chromogranin-A, CgA, Pituitary secretory protein I, SP-I
Background: The protein encoded byThis gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides, vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Two other peptides, catestatin and chromofungin, have antimicrobial activity and antifungal activity, respectively. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014],
Gene Name: CHGA
Protein Name: Chromogranin-A
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分子量
- 50 kDa
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基因ID
- 1113
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OMIM
- 118910
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UniProt
- P10645
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途径
- Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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