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Cathepsin D 抗体 (AA 296-345)

The 兔 多克隆 anti-Cathepsin D antibody is suitable to detect Cathepsin D in samples from 人, 大鼠 和 小鼠. It has been validated for WB, IHC, ELISA 和 IF.
产品编号 ABIN1453035
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for Cathepsin D 抗体 (AA 296-345) (ABIN1453035)

抗原

See all Cathepsin D (CTSD) 抗体
Cathepsin D (CTSD)

适用

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人, 大鼠, 小鼠

宿主

  • 161
  • 67
  • 2
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兔

克隆类型

  • 138
  • 91
多克隆

标记

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This Cathepsin D antibody is un-conjugated

应用范围

  • 197
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 45
    • 15
    • 12
    • 12
    • 12
    • 12
    • 9
    • 8
    • 5
    • 5
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    AA 296-345

    原理

    Cathepsin D Antibody

    特异性

    Cathepsin D Polyclonal Antibody detects endogenous levels of Cathepsin D protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized peptide derived from human Cathepsin D. AA range:296-345

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Cathepsin D (CTSD)

    别名

    Cathepsin D

    背景

    Synonyms: CTSD; CPSD; Cathepsin D

    Background: This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015],

    Gene Name: CTSD

    Protein Name: Cathepsin D

    分子量

    44 kDa

    基因ID

    1509

    OMIM

    116840

    UniProt

    P07339

    途径

    Peptide Hormone Metabolism
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