CAD 抗体
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北京 101111
Quick Overview for CAD 抗体 (ABIN1453005)
抗原
See all CAD 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- DFFB Antibody
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特异性
- This antibody detects endogenous levels of human DFFB
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human DFFB
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亚型
- IgG
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anti-Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) (AA 780-809) antibody
CAD 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB18384 unconjugated
anti-Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) (AA 1650-1900) antibodyCAD 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) antibodyCAD 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) antibodyKD Validated CAD 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2240 unconjugated Recombinant Antibody
anti-Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) (AA 1403-2198) antibodyCAD 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) (AA 780-809) antibodyCAD 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) (AA 1650-1700) antibodyCAD 适用: 人 IHC, IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) antibodyCAD 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) (C-Term) antibodyCAD 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) antibodyCAD 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC 1:50-200, WB 1:500-2000. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- CAD (Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD))
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别名
- CAD
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背景
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Synonyms: DNA fragmentation factor subunit beta (EC 3.-.-.-, Caspase-activated deoxyribonuclease, CAD, Caspase-activated DNase, Caspase-activated nuclease, CPAN, DNA fragmentation factor 40 kDa subunit, DFF-40)
Background: Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene but the biological validity of some of these variants has not been determined. [provided by RefSeq, Sep 2013],
Gene Name: DFFB CAD DFF2 DFF40
Protein Name: DFFB
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分子量
- 39 kDa
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基因ID
- 1677
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OMIM
- 601883
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UniProt
- O76075
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途径
- Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process
抗原
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