BMP8B 抗体 (AA 41-90)
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北京 101111
Quick Overview for BMP8B 抗体 (AA 41-90) (ABIN1452978)
抗原
See all BMP8B (BMP8) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 41-90
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原理
- BMP-8 Antibody
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特异性
- BMP-8 Polyclonal Antibody detects endogenous levels of BMP-8 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human BMP-8. AA range:41-90
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亚型
- IgG
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应用备注
- IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- BMP8B (BMP8) (Bone Morphogenetic Protein 8B (BMP8))
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别名
- BMP-8
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背景
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Synonyms: BMP8B, BMP8, Bone morphogenetic protein 8B, BMP-8, BMP-8B, Osteogenic protein 2, OP-2, BMP8A, Bone morphogenetic protein 8A, BMP-8A
Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The encoded protein stimulates thermogenesis in brown adipose tissue. Expression of this gene may be downregulated in pancreatic cancer. This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1. [provided by RefSeq, Jul 2016],
Gene Name: BMP8A/BMP8B
Protein Name: Bone morphogenetic protein 8A/B
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分子量
- 44 kDa
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基因ID
- 656
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OMIM
- 602284
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UniProt
- P34820
抗原
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