BMP5 抗体 (AA 114-163)
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北京 101111
Quick Overview for BMP5 抗体 (AA 114-163) (ABIN1452969)
抗原
See all BMP5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 114-163
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原理
- BMP-5 Antibody
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特异性
- BMP-5 Polyclonal Antibody detects endogenous levels of BMP-5 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human BMP-5. AA range:114-163
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- BMP5 (Bone Morphogenetic Protein 5 (BMP5))
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别名
- BMP-5
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背景
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Synonyms: BMP5, Bone morphogenetic protein 5, BMP-5
Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Polymorphisms in this gene may be associated with osteoarthritis in human patients. This gene is differentially regulated in multiple human cancers.This gene encodes distinct protein isoforms that may be similarly proteolytically processed. [provided by RefSeq, Jul 2016],
Gene Name: BMP5
Protein Name: Bone morphogenetic protein 5
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分子量
- 51 kDa
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基因ID
- 653
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OMIM
- 112265
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UniProt
- P22003
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途径
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process
抗原
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