ITIH2 抗体 (Cleaved-Asp702)
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北京 101111
Quick Overview for ITIH2 抗体 (Cleaved-Asp702) (ABIN1452255)
抗原
See all ITIH2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 653-702, Cleaved-Asp702
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原理
- Cleaved-ITI-H2 (D702) Antibody
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特异性
- Cleaved-ITI-H2 (D702) Polyclonal Antibody detects endogenous levels of fragment of activated ITI-H2 protein resulting from cleavage adjacent to D702.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human ITIH2. AA range:653-702
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- ITIH2 (Inter-alpha Globulin Inhibitor H2 Polypeptide (ITIH2))
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别名
- ITIH2
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背景
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Synonyms: ITIH2, IGHEP2, Inter-alpha-trypsin inhibitor heavy chain H2, ITI heavy chain H2, ITI-HC2, Inter-alpha-inhibitor heavy chain 2, Inter-alpha-trypsin inhibitor complex component II, Serum-derived hyaluronan-associated protein, SHAP
Background: The inter-alpha-trypsin inhibitors (ITI) are a family of structurally related plasma serine protease inhibitors involved in extracellular matrix stabilization and in prevention of tumor metastasis. The ITI family contains multiple proteins made up of a light chain (see MIM 176870) and a variable number of heavy chains (Salier et al., 1987 [PubMed 2446322], Himmelfarb et al., 2004 [PubMed 14744536]).[supplied by OMIM, Nov 2009],
Gene Name: ITIH2
Protein Name: Inter-alpha-trypsin inhibitor heavy chain H2
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分子量
- 106 kDa
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基因ID
- 3698
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OMIM
- 146640
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UniProt
- P19823
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途径
- Glycosaminoglycan Metabolic Process
抗原
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