VASH1 抗体 (AA 261-310)
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北京 101111
Quick Overview for VASH1 抗体 (AA 261-310) (ABIN1452171)
抗原
See all VASH1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 261-310
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原理
- Vasohibin Antibody
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特异性
- Vasohibin Polyclonal Antibody detects endogenous levels of Vasohibin protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human VASH1. AA range:261-310
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亚型
- IgG
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anti-Vasohibin 1 (VASH1) (AA 3-100) antibody
VASH1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4A3 unconjugated
anti-Vasohibin 1 (VASH1) (AA 1-204) antibodyVASH1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Vasohibin 1 (VASH1) antibodyVASH1 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 25GB720 unconjugated
anti-Vasohibin 1 (VASH1) (AA 281-365) antibodyVASH1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Vasohibin 1 (VASH1) (AA 72-121) antibodyVASH1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Vasohibin 1 (VASH1) (AA 108-157) antibodyVASH1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Hamster, 猴, Pig, Bat, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Vasohibin 1 (VASH1) (N-Term) antibodyVASH1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Vasohibin 1 (VASH1) (Internal Region) antibodyVASH1 适用: 人, 小鼠, 大鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vasohibin 1 (VASH1) (AA 3-101) antibodyVASH1 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4A3 unconjugated
anti-Vasohibin 1 (VASH1) (Internal Region) antibodyVASH1 适用: 人 WB 宿主: 小鼠 Monoclonal AFfirm9375 unconjugated
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- VASH1 (Vasohibin 1 (VASH1))
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别名
- VASH1
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背景
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Synonyms: VASH1, KIAA1036, VASH, Vasohibin-1
Background: caution:Although probably secreted, it lacks a canonical signal sequence.,function:Angiogenesis inhibitor. Inhibits migration, proliferation and network formation by endothelial cells as well as angiogenesis. This inhibitory effect is selective to endothelial cells as it does not affect the migration of smooth muscle cells or fibroblasts. Does not affect the proliferation of cancer cells in vitro, but inhibits tumor growth and tumor angiogenesis. Acts in an autocrine manner. Inhibits artery neointimal formation and macrophage infiltration. Exhibits heparin-binding activity.,induction:By VEGF.,PTM:2 major forms (42 and 36 kDa) and 2 minors (32 and 27 kDa) may be processed by proteolytic cleavage. The largest form (42 kDa) seems to be secreted and the other major form (63 kDa) seems to accumulate within the cells or pericellular milieu. Polypeptide consisting of Met-77 to Arg-318 may correspond to the 27 kDa form and that consisting of Met-77 to Val-365 may correspond to the 36 kDa form.,similarity:Belongs to the vasohibin family.,tissue specificity:Preferentially expressed in endothelial cells. Highly expressed in fetal organs. Expressed in brain and placenta, and at lower level in heart and kidney. Highly detected in microvessels endothelial cells of atherosclerotic lesions.,
Gene Name: VASH1
Protein Name: Vasohibin-1
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分子量
- 40 kDa
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基因ID
- 22846
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OMIM
- 609011
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UniProt
- Q7L8A9
抗原
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