Desmoglein 1 抗体 (AA 161-210)
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北京 101111
Quick Overview for Desmoglein 1 抗体 (AA 161-210) (ABIN1452168)
抗原
See all Desmoglein 1 (DSG1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 161-210
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原理
- Dsg1 Antibody
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特异性
- Dsg1 Polyclonal Antibody detects endogenous levels of Dsg1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human DSG1. AA range:161-210
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亚型
- IgG
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anti-Desmoglein 1 (DSG1) antibody
DSG1 适用: 人 IHC 宿主: 小鼠 Monoclonal 32-2B unconjugated
anti-Desmoglein 1 (DSG1) antibodyDSG1 适用: 人 IHC 宿主: 小鼠 Monoclonal 544M unconjugated
anti-Desmoglein 1 (DSG1) antibodyDSG1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Desmoglein 1 (DSG1) (AA 800-1049) antibodyDSG1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Desmoglein 1 (DSG1) (AA 384-539) antibodyDSG1 适用: 人 IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Desmoglein 1 (DSG1) (AA 1-1049) antibodyDSG1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Desmoglein 1 (DSG1) (AA 1-1049) antibodyDSG1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Desmoglein 1 (DSG1) (Internal Region) antibodyVerified DSG1 适用: 人 IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Desmoglein 1 (DSG1) (Intracellular) antibodyDSG1 适用: 人 WB, IF, FACS 宿主: 小鼠 Monoclonal 18D4 unconjugated
anti-Desmoglein 1 (DSG1) (Intracellular) antibodyDSG1 适用: 人 IHC 宿主: 小鼠 Monoclonal DSG1-1733 unconjugated
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Desmoglein 1 (DSG1)
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别名
- DSG1
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背景
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Synonyms: DSG1, CDHF4, Desmoglein-1, Cadherin family member 4, Desmosomal glycoprotein 1, DG1, DGI, Pemphigus foliaceus antigen
Background: This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma. [provided by RefSeq, Feb 2015],
Gene Name: DSG1
Protein Name: Desmoglein-1
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分子量
- 113 kDa
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基因ID
- 1828
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OMIM
- 125670
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UniProt
- Q02413
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途径
- Cell-Cell Junction Organization
抗原
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