ERI1 抗体 (AA 261-310)
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Quick Overview for ERI1 抗体 (AA 261-310) (ABIN1452117)
抗原
See all ERI1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 261-310
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原理
- ERI1 Antibody
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特异性
- ERI1 Polyclonal Antibody detects endogenous levels of ERI1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human ERI1. AA range:261-310
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亚型
- IgG
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anti-Exoribonuclease 1 (ERI1) antibody
ERI1 适用: 人, 大鼠, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1B3 unconjugated
anti-Exoribonuclease 1 (ERI1) (AA 2-66) antibodyERI1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Exoribonuclease 1 (ERI1) antibodyERI1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Exoribonuclease 1 (ERI1) (AA 51-150) antibodyERI1 适用: 人 IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Exoribonuclease 1 (ERI1) (AA 1-345) antibodyERI1 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Exoribonuclease 1 (ERI1) (N-Term) antibodyERI1 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Exoribonuclease 1 (ERI1) (AA 29-78) antibodyERI1 适用: 人, 犬, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Exoribonuclease 1 (ERI1) (AA 231-280) antibodyERI1 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Exoribonuclease 1 (ERI1) (C-Term) antibodyERI1 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Exoribonuclease 1 (ERI1) (C-Term) antibodyERI1 适用: 人, 小鼠, 大鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- ERI1 (Exoribonuclease 1 (ERI1))
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别名
- ERI1
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背景
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Synonyms: ERI1, 3'EXO, THEX1, 3'-5' exoribonuclease 1, 3'-5' exonuclease ERI1, Eri-1 homolog, Histone mRNA 3'-end-specific exoribonuclease, Histone mRNA 3'-exonuclease 1, Protein 3'hExo, HEXO
Background: cofactor:Binds 2 magnesium ions per subunit.,enzyme regulation:Although it can bind simultaneously with SLBP to the 3'-end of histone mRNA, the presence of SLBP prevents the exonuclease activity.,function:RNA exonuclease that binds to the 3'-end of histone mRNAs and probably degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Required for 5.8S rRNA 3'-end processing.,sequence caution:Translated as Leu.,similarity:Contains 1 exonuclease domain.,similarity:Contains 1 SAP domain.,subunit:Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs. Requires the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Binds to 40S and 60S ribosomal subunits and to 80S assembled ribosomes. Also binds to 5.8s ribosomal RNA.,
Gene Name: ERI1
Protein Name: 3'-5' exoribonuclease 1
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分子量
- 40 kDa
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基因ID
- 90459
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OMIM
- 608739
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UniProt
- Q8IV48
抗原
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