BUB1 抗体 (AA 781-830)
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北京 101111
Quick Overview for BUB1 抗体 (AA 781-830) (ABIN1452063)
抗原
See all BUB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 781-830
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原理
- BUB1 Antibody
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特异性
- BUB1 Polyclonal Antibody detects endogenous levels of BUB1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human BUB1. AA range:781-830
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- BUB1 (Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1))
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别名
- BUB1
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背景
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Synonyms: BUB1, BUB1L, Mitotic checkpoint serine/threonine-protein kinase BUB1, hBUB1, BUB1A
Background: This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
Gene Name: BUB1
Protein Name: Mitotic checkpoint serine/threonine-protein kinase BUB1
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分子量
- 122 kDa
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基因ID
- 699
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OMIM
- 602452
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UniProt
- O43683
抗原
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