TRAF4 抗体 (AA 261-310)
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Quick Overview for TRAF4 抗体 (AA 261-310) (ABIN1451997)
抗原
See all TRAF4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 261-310
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原理
- TRAF4 Antibody
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特异性
- TRAF4 Polyclonal Antibody detects endogenous levels of TRAF4 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human TRAF4. AA range:261-310
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- TRAF4 (TNF Receptor-Associated Factor 4 (TRAF4))
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别名
- TRAF4
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背景
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Synonyms: TRAF4, CART1, MLN62, RNF83, TNF receptor-associated factor 4, Cysteine-rich domain associated with RING and Traf domains protein 1, Metastatic lymph node gene 62 protein, MLN 62, RING finger protein 83
Background: TNF receptor associated factor 4(TRAF4) Homo sapiens This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008],
Gene Name: TRAF4
Protein Name: TNF receptor-associated factor 4
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分子量
- 53 kDa
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基因ID
- 9618
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OMIM
- 602464
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UniProt
- Q9BUZ4
抗原
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