IL17RC 抗体 (AA 721-770)
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北京 101111
Quick Overview for IL17RC 抗体 (AA 721-770) (ABIN1451946)
抗原
See all IL17RC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 721-770
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原理
- IL-17RC Antibody
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特异性
- IL-17RC Polyclonal Antibody detects endogenous levels of IL-17RC protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human IL17RC. AA range:721-770
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- IL17RC (Interleukin 17 Receptor C (IL17RC))
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别名
- IL17RC
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背景
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Synonyms: IL17RC, Interleukin-17 receptor C, IL-17 receptor C, IL-17RC, Interleukin-17 receptor homolog, IL17Rhom, Interleukin-17 receptor-like protein, IL-17RL, ZcytoR14
Background: This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling. [provided by RefSeq, Feb 2011],
Gene Name: IL17RC
Protein Name: Interleukin-17 receptor C
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分子量
- 86 kDa
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基因ID
- 84818
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OMIM
- 610925
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UniProt
- Q8NAC3
抗原
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