TAO Kinase 3 抗体 (AA 531-580)
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北京 101111
Quick Overview for TAO Kinase 3 抗体 (AA 531-580) (ABIN1451898)
抗原
See all TAO Kinase 3 (TAOK3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 531-580
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原理
- JIK Antibody
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特异性
- JIK Polyclonal Antibody detects endogenous levels of JIK protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human TAOK3. AA range:531-580
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亚型
- IgG
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应用备注
- WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- TAO Kinase 3 (TAOK3)
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别名
- TAOK3
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背景
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Synonyms: TAOK3, DPK, JIK, KDS, MAP3K18, Serine/threonine-protein kinase TAO3, Cutaneous T-cell lymphoma-associated antigen HD-CL-09, CTCL-associated antigen HD-CL-09, Dendritic cell-derived protein kinase, JNK/SAPK-inhibitory kinase, Jun kinase-inhi
Background: catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Inhibits the basal activity of Jun kinase. Negatively regulated by epidermal growth factor (EGF). When overexpressed, may activate ERK1/ERK2 and JNK/SAPK.,PTM:Autophosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,subcellular location:Also localized to the peripheral cell membrane.,subunit:Self-associates.,tissue specificity:Ubiquitously expressed at a low level, and highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver.,
Gene Name: TAOK3
Protein Name: Serine/threonine-protein kinase TAO3
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分子量
- 105 kDa
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基因ID
- 51347
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UniProt
- Q9H2K8
抗原
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