ARHGEF11 抗体 (AA 198-247)
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Quick Overview for ARHGEF11 抗体 (AA 198-247) (ABIN1451559)
抗原
See all ARHGEF11 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 198-247
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原理
- PDZ-RhoGEF Antibody
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特异性
- PDZ-RhoGEF Polyclonal Antibody detects endogenous levels of PDZ-RhoGEF protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human ARHGEF11. AA range:198-247
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亚型
- IgG
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应用备注
- WB 1:500-2000,IHC 1:50-300
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- ARHGEF11 (rho Guanine Nucleotide Exchange Factor (GEF) 11 (ARHGEF11))
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别名
- ARHGEF11
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背景
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Synonyms: ARHGEF11, KIAA0380, Rho guanine nucleotide exchange factor 11, PDZ-RhoGEF
Background: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008],
Gene Name: ARHGEF11
Protein Name: Rho guanine nucleotide exchange factor 11
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分子量
- 167 kDa
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基因ID
- 9826
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OMIM
- 605708
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UniProt
- O15085
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途径
- Neurotrophin Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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