Repetin 抗体 (AA 648-697)
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北京 101111
Quick Overview for Repetin 抗体 (AA 648-697) (ABIN1451544)
抗原
See all Repetin (RPTN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 648-697
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原理
- Repetin Antibody
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特异性
- Repetin Polyclonal Antibody detects endogenous levels of Repetin protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human RPTN. AA range:648-697
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亚型
- IgG
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应用备注
- WB 1:500-2000,IHC 1:50-300
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Repetin (RPTN)
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别名
- RPTN
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背景
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Synonyms: RPTN, Repetin
Background: domain:Can be divided into a N-terminal domain with significant homology to S100-like calcium-binding proteins, a central domain containing a series of short tandem repeats, and two flanking segments with low homology to the consensus sequences of the central repeats.,function:Involved in the cornified cell envelope formation. Multifunctional epidermal matrix protein. Reversibly binds calcium.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,PTM:Potential substrate of transglutaminase. Some arginines are probably converted to citrullines by peptidylarginine deimidase.,similarity:Belongs to the S100-fused protein family.,similarity:Contains 2 EF-hand domains.,tissue specificity:Expression is scattered in the normal epidermis but strong in the acrosyringium, the inner hair root sheat and in the filiform papilli of the tongue.,
Gene Name: RPTN
Protein Name: Repetin
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分子量
- 90 kDa
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基因ID
- 126638
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UniProt
- Q6XPR3
抗原
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