RGS10 抗体 (AA 80-129)
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北京 101111
Quick Overview for RGS10 抗体 (AA 80-129) (ABIN1451532)
抗原
See all RGS10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 80-129
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原理
- RGS10 Antibody
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特异性
- RGS10 Polyclonal Antibody detects endogenous levels of RGS10 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human RGS10. AA range:80-129
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- RGS10 (Regulator of G-Protein Signaling 10 (RGS10))
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别名
- RGS10
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背景
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Synonyms: RGS10, Regulator of G-protein signaling 10, RGS10
Background: Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 10 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein associates specifically with the activated forms of the two related G-protein subunits, G-alphai3 and G-alphaz but fails to interact with the structurally and functionally distinct G-alpha subunits. Regulator of G protein signaling 10 protein is localized in the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Gene Name: RGS10
Protein Name: Regulator of G-protein signaling 10
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分子量
- 20 kDa
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基因ID
- 6001
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OMIM
- 602856
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UniProt
- O43665
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途径
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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