RASA3 抗体 (AA 247-296)
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北京 101111
Quick Overview for RASA3 抗体 (AA 247-296) (ABIN1451505)
抗原
See all RASA3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 247-296
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原理
- GAP1-InsP4 BP Antibody
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特异性
- GAP1-InsP4 BP Polyclonal Antibody detects endogenous levels of GAP1-InsP4 BP protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human RASA3. AA range:247-296
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- RASA3 (RAS P21 Protein Activator 3 (RASA3))
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别名
- RASA3
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背景
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Synonyms: RASA3, Ras GTPase-activating protein 3, GAP1(IP4BP), Ins P4-binding protein
Background: This gene encodes a protein that binds inositol 1,3,4,5-tetrakisphosphate and stimulates the GTPase activity of Ras p21. This protein functions as a negative regulator of the Ras signalling pathway. It is localized to the cell membrane via a pleckstrin homology (PH) domain in the C-terminal region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],
Gene Name: RASA3
Protein Name: Ras GTPase-activating protein 3
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分子量
- 95 kDa
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基因ID
- 22821
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OMIM
- 605182
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UniProt
- Q14644
抗原
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