RAPGEF3 抗体 (AA 712-761)
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北京 101111
Quick Overview for RAPGEF3 抗体 (AA 712-761) (ABIN1451502)
抗原
See all RAPGEF3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 712-761
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原理
- Epac Antibody
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特异性
- Epac Polyclonal Antibody detects endogenous levels of Epac protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human RAPGEF3. AA range:712-761
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- RAPGEF3 (Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3))
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别名
- RAPGEF3
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背景
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Synonyms: RAPGEF3, CGEF1, EPAC, EPAC1, Rap guanine nucleotide exchange factor 3, Exchange factor directly activated by cAMP 1, Exchange protein directly activated by cAMP 1, EPAC 1, Rap1 guanine-nucleotide-exchange factor directly activated by cAMP,
Background: caution:It is uncertain whether Met-1 or Met-43 is the initiator.,domain:The DEP domain is involved in membrane localization independent from regulation by cAMP.,function:Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP.,similarity:Contains 1 cyclic nucleotide-binding domain.,similarity:Contains 1 DEP domain.,similarity:Contains 1 N-terminal Ras-GEF domain.,similarity:Contains 1 Ras-GEF domain.,tissue specificity:Widely expressed with highest levels in adult kidney, heart, thyroid and brain, and fetal kidney.,
Gene Name: RAPGEF3
Protein Name: Rap guanine nucleotide exchange factor 3
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分子量
- 99 kDa
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基因ID
- 10411
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OMIM
- 606057
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UniProt
- O95398
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途径
- cAMP Metabolic Process
抗原
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