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PDHA1 抗体 (AA 314-363)

The 兔 多克隆 anti-PDHA1 antibody (ABIN1451481) specifically detects PDHA1 in WB, IHC, ELISA 和 IF. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN1451481
发货至: 中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PDHA1 抗体 (AA 314-363) (ABIN1451481)

抗原

See all PDHA1 抗体
PDHA1 (Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1))

适用

  • 120
  • 48
  • 46
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 110
  • 12
兔

克隆类型

  • 81
  • 41
多克隆

标记

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  • 2
  • 2
  • 2
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  • 2
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  • 1
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  • 1
This PDHA1 antibody is un-conjugated

应用范围

  • 103
  • 36
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  • 21
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  • 15
  • 13
  • 13
  • 5
  • 3
  • 1
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 32
    • 15
    • 7
    • 7
    • 7
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 314-363

    原理

    PDHA1 Antibody

    特异性

    PDHA1 Polyclonal Antibody detects endogenous levels of PDHA1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized peptide derived from human PDHA1. AA range:314-363

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    PDHA1 (Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1))

    别名

    PDHA1

    背景

    Synonyms: PDHA1, PHE1A, Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial, PDHE1-A type I

    Background: The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits.This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010],

    Gene Name: PDHA1 ODPA

    Protein Name: Pyruvate dehydrogenase E1 component subunit alpha somatic form mitochondrial

    分子量

    43 kDa

    基因ID

    5160

    OMIM

    300502

    UniProt

    P08559

    途径

    Warburg Effect
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