SLC16A2/MCT8 抗体 (AA 112-161)
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Quick Overview for SLC16A2/MCT8 抗体 (AA 112-161) (ABIN1451355)
抗原
See all SLC16A2/MCT8 (SLC16A2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 112-161
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原理
- MCT8 Antibody
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特异性
- MCT8 Polyclonal Antibody detects endogenous levels of MCT8 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human SLC16A2. AA range:112-161
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- SLC16A2/MCT8 (SLC16A2) (Solute Carrier Family 16 Member 2 (SLC16A2))
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别名
- SLC16A2
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背景
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Synonyms: SLC16A2, MCT8, XPCT, Monocarboxylate transporter 8, MCT 8, Monocarboxylate transporter 7, MCT 7, Solute carrier family 16 member 2, X-linked PEST-containing transporter
Background: This gene encodes an integral membrane protein that functions as a transporter of thyroid hormone. The encoded protein facilitates the cellular importation of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and diidothyronine (T2). This gene is expressed in many tissues and likely plays an important role in the development of the central nervous system. Loss of function mutations in this gene are associated with psychomotor retardation in males while females exhibit no neurological defects and more moderate thyroid-deficient phenotypes. This gene is subject to X-chromosome inactivation. Mutations in this gene are the cause of Allan-Herndon-Dudley syndrome. [provided by RefSeq, Mar 2012],
Gene Name: SLC16A2
Protein Name: Monocarboxylate transporter 8
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分子量
- 59 kDa
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基因ID
- 6567
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OMIM
- 300095
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UniProt
- P36021
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途径
- Hormone Transport
抗原
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