GLRB 抗体 (AA 211-260)
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北京 101111
Quick Overview for GLRB 抗体 (AA 211-260) (ABIN1451271)
抗原
See all GLRB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 211-260
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原理
- GlyRβ Antibody
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特异性
- GlyRβ Polyclonal Antibody detects endogenous levels of GlyRβ protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human GLRB. AA range:211-260
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- GLRB (Glycine Receptor, beta (GLRB))
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别名
- GLRB
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背景
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Synonyms: GLRB, Glycine receptor subunit beta, Glycine receptor 58 kDa subunit
Background: This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],
Gene Name: GLRB
Protein Name: Glycine receptor subunit beta
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分子量
- 56 kDa
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基因ID
- 2743
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OMIM
- 138492
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UniProt
- P48167
抗原
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