CNGA1 抗体 (AA 401-450)
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北京 101111
Quick Overview for CNGA1 抗体 (AA 401-450) (ABIN1451154)
抗原
See all CNGA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 401-450
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原理
- CNG-1 Antibody
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特异性
- CNG-1 Polyclonal Antibody detects endogenous levels of CNG-1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human CNGA1. AA range:401-450
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- CNGA1 (Cyclic Nucleotide Gated Channel alpha 1 (CNGA1))
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别名
- CNGA1
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背景
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Synonyms: CNGA1, CNCG, CNCG1, cGMP-gated cation channel alpha-1, Cyclic nucleotide-gated cation channel 1, Cyclic nucleotide-gated channel alpha-1, CNG channel alpha-1, CNG-1, CNG1, Cyclic nucleotide-gated channel, photoreceptor, Rod photoreceptor cG
Background: The protein encoded by this gene is involved in phototransduction. Along with another protein, the encoded protein forms a cGMP-gated cation channel in the plasma membrane, allowing depolarization of rod photoreceptors. This represents the last step in the phototransduction pathway. Defects in this gene are a cause of retinitis pigmentosa autosomal recessive (ARRP) disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008],
Gene Name: CNGA1
Protein Name: cGMP-gated cation channel alpha-1
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分子量
- 79 kDa
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基因ID
- 1259
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OMIM
- 123825
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UniProt
- P29973
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction, Asymmetric Protein Localization
抗原
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